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Dr. Thomas Brandstetter

Dr. Thomas BrandstetterDr. Thomas Brandstetter studied Biology at the University of Freiburg. He received his Ph.D. in 2000 working with Prof. Dr. Wagner at the Institute for Biology II and Prof. Dr. Wieland at the University hospital, Department for Clinical chemistry (oncology). Subse-quently he moved on to a position as a postdoctoral associate working on microarray applications for clinical and diagnostic purposes in cooperation with the company “Genescan Europe AG”, a biochip company. After becoming safety officer for medical devices he entered the group of Prof. Dr. Rühe at the Department for Microsystems Engineering (IMTEK), at the University of Freiburg in 2005. Since 2007 he is group leader for Biochip technologies and bioanalytical surfaces.

Research interests:
  • Developing new detection methods for SNP and genexpression analysis
  • Direct labeling of RNA and DNA
  • On chip real time measurment
  • Developing new surfaces for increased sensitivity and stability
  • Reusable and standarized biochips
 

Public Profile:

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Selected Publications

  • Rendl M., Bönisch A., Mader A., Schuh K., Prucker O., Brandstetter T. and Rühe J.. A Simple One-Step Procedure for Immobilization of Biomolecules on Plastic Surfaces using Surface-Attached Polymer Networks. Langmuir, 2011, 27 (10), pp 6116–6123 [PMID:21491877]
  • Mader A., Riehle U., Brandstetter T., Stickeler E., zur Hausen A. and Rühe J.. Microarray- based Amplification and Detection of RNA by Nucleic Acid Sequence-Based Amplification (NASBA). Analytical Bioanalytical Chemistry 2010; 397(8), 3533-3541. [PMID: 20596698]
  • Brandstetter T., Böhmer S., Prucker O., Bissé E., zur Hausen A., Alt-Mörbe J. and Rühe, J. (2009) A Polymer-based DNA Biochip Platform for Human Papilloma Virus Genotyping. J Virol Methods. 2010 Jan;163(1):40-8. Epub 2009 Aug 5. [PMID: 19664659]
  • Schenk T., Brandstetter T., zur Hausen A., Alt-Mörbe J., Huzly D. and Rühe J. (2009) Performance of a polymer-based DNA chip platform in detection and genotyping of human papillomavirus in clinical samples. J Clin Microbiol.; 47(5):1428-35. [PMID: 19279180]
  • Thomas Brandstetter, Elena Ninci, Herta Bettendorf, Gloria Perewusnyk, Jens Stolte, Dieter Herchenbach, Dieter Sellin, Edgar Wagner, Ossi R., Köchli, Edgar Wagner and Thomas Bauknecht (2001): Granulocyte Colony-Stimulating Factor (G-CSF) Gene Expression of Ovarian Carcinoma Does not Correlate with G-CSF Caused Cell Proliferation. Cancer, 91; 1372-1383. [PMID:11283939]
  • T. Brandstetter, E. Ninci, U. Falken, E. Wagner, R.D. Hess and T. Bauknecht (1998): rhG-CSF Affects Genes Involved In Mitogen Signalling And Early Gene Expression In the Ovarian Cancer Cell line HEY. Int. J. Cancer 75, 847 - 854. [PMID: 9506529]

 

Contact

Dr. Thomas Brandstetter

University of Freiburg - IMTEK
Department of Microsystems Engineering
Laboratory for Chemistry and Physics of Interfaces

Georges-Koehler-Allee 103
D-79110 Freiburg, Germany

Tel.: +49 761 203 - 7163 (office)
Tel.: +49 761 203 - 7181 (lab)
Fax: +49 761 203 - 7162
brandstetter@imtek.uni-freiburg.de

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