Welcome to CPI - Chemistry & Physics of Interfaces



About us


The Rühe group investigates the development of strategies for generating tailormade surfaces. We develop new chemical methods to attach polymers to surfaces and combine them with methods of nano and micro structuring to produce novel metamaterials and interactive materials. Fields of applications are biointerfaces (cell adhesion, biofouling; lab-on-chip, hydrogels), optics, tribology, living materials systems, and surfaces with unusual wetting behavior.




Prof. Dr. Jürgen Rühe
University of Freiburg - IMTEK
Department of Microsystems Engineering
Chemistry and Physics of Interfaces
Georges-Koehler-Allee 103 / Rm 00 109
D-79110 Freiburg, Germany

Tel.: +49 761  203 7160 (secretary)
Tel.: +49 761  203 7161 (direct)
Fax: +49 761  203 7162
Email: ruehe@imtek.uni-freiburg.de


Recent Publications


Dan Song, Ayman Husari, Frederik Kotz-Helmer, Pascal Tomakidi, Bastian E. Rapp, Jürgen Rühe
Two-Photon Direct Laser Writing of 3D Scaffolds through C, H-Insertion Crosslinking in a One-Component Material System
Small 2023, 2306682
DOI: 10.1002/smll.202306682

Lokman Alpsoy, Abanoub Selim Sedeky, Ulrike Rehbein, Kathrin Thedieck, Thomas Brandstetter, and Jürgen Rühe
Particle ID: A Multiplexed Hydrogel Bead Platform for Biomedical Applications
ACS Appl. Mater. Interfaces 2023, 15, 48, 55346–55357
DOI: 10.1021/acsami.3c12122

Anna Luongo, Alexander Ritter von Stockert, Frank D. Scherag, Thomas Brandstetter, Markus Biesalski, and Jürgen Rühe
Controlling Fluorescent Readout in Paper-based Analytical Devices
ACS Biomater. Sci. Eng. 2023, 9, 11, 6379–6389.
DOI: 10.1021/acsbiomaterials.3c00736

Felix Joachim Gatti, Wanhao Cai, Richard Herzog, Amirmasoud Gharavian, Andreas Kailer, Norman Baltes, Peter Rabenecker, Philipp Mörchel, Bizan N Balzer, Tobias Amann, Jürgen Rühe
Investigation of programmable friction with ionic liquid mixtures at the nano-and macroscales
Lubricants 2023, 11, 376
DOI: 10.3390/lubricants11090376

Dennis Rusitov, Florian Deussen, and Jürgen Rühe
Fast UV- and Visible Light Induced Polymer Network Formation Using Carbene Mediated C–H-insertion Based Crosslinking (CHic) Via Nitrophenyl Diazo Esters
Advanced Materials Interfaces 2023, 10, 2300316
DOI: 10.1002/admi.202300316

Lena Mungenast, Ronya Nieminen, Carine Gaiser, Ana Bela Faia-Torres, Jürgen Rühe, and Laura Suter-Dick
Electrospun decellularized extracellular matrix scaffolds promote the
regeneration of injured neurons

Biomaterials and Biosystems 2023, 11, 1000081
DOI: 10.1016/j.bbiosy.2023.100081

Carina Ludwig, Jan Leutner, Oswald Prucker, Jürgen Rühe and Manfred Kohl
Miniature-scale elastocaloric cooling by rubber-based foils
Jounal of Physics: Energy 2023, 6, 015009
DOI: 10.1088/2515-7655/ad0cff

Nicolas Geid, Jan Ulrich Leutner, Oswald Prucker and Jürgen Rühe
Maskless Writing of Surface-Attached Micro-Magnets by Two-Photon Crosslinking
Actuators 2023, 12, 124.
DOI: 10.3390/act12030124

Samuel Franz Gatti, Felix Gatti, Tobias Amann, Andreas Kailer, Kevin Moser, Patrick Weiss, Claudia Seidel, and Jürgen Rühe
Tribological performance of electrically conductive and self-lubricating polypropylene–ionic-liquid composites
RSC Advances, 2023, 13, 8000-8014.
DOI: 10.1039/D3RA00712J

Suresh Reddy Banda, Holger Klapproth, Nicolaas Smit, Sonja Bednar, Thomas Brandstetter, and Jürgen Rühe
An advanced and efficient asymmetric PCR method for microarray applications
Frontiers in Bioengineering and Biotechnology 2022, 10, 1045154.
DOI: 10.3389/fbioe.2022.1045154


Maryam Bahrami, Vincent Le Houérou, and Jürgen Rühe
Lubrication Mechanism of Surface-Attached Hydrogel Layers in Sliding Contact
Advanced Materials Interfaces 2022, 9, 2201581.
DOI: 10.1002/admi.202201581

Dan Song, Frederik Kotz-Helmer, Bastian Rapp, and Jürgen Rühe
Substrate-Independent Maskless Writing of Functionalized Microstructures Using CHic Chemistry and Digital Light Processing
ACS Applied Material Interfaces 2022, 14, 50288–50295.
DOI: 10.1021/acsami.2c12000

Lena Mungenast, Fabian Züger, Jasmin Selvi, Ana Bela Faia-Torres, Jürgen Rühe, Laura Suter-Dick, and Maurizio R. Gullo
Directional Submicrofiber Hydrogel Composite Scaffolds Supporting Neuron Differentiation and Enabling Neurite Alignmen
International Journal of  Molecular Sciences 2022, 23, 11525.
DOI: 10.3390/ijms231911525

Anil Rajak, Jürgen Rühe
High Hysteresis Suspended Wetting State: A Wetting Regime for Controlled Trapping of Drops on Micro-Trench Covered Surfaces
Advanced Materials Interfaces 2022, 9, 2201018.
DOI: 10.1002/admi.202201018


Alexander Bleiziffer, Jonas Kost, Jürgen Rühe
Thermal Structuring of Surface-Attached Polymer Networks by C,H Insertion Reactions
Macromolecular Materials and Engineering 2022, 307, 2200345.
DOI: 10.1002/mame.202200345

Retno Ardhani, Tiyastiti Suraya, Martha Purnami Wulanjati, Ika Dewi Ana, Jürgen Rühe, and Bidhari Pidhatika
Photoreactive polymer and C,H-insertion reaction to tailor the properties of CHA/gelatin-based scaffold
International Journal of Polymer Analysis and Characterization 2022, 27, 326-345.
DOI: 10.1080/1023666X.2022.2076012

Stefan Müllers, Mara Florea-Hüring, Bernhard von Vacano, Bernd Bruchmann, Jürgen Rühe
Hairy surfaces by cold drawing leading to dense lawns of high aspect ratio hairs
Scientific Reports 2022, 12, 9952
DOI: 10.1038/s41598-022-13419-3

Müller porous template

Tobias A. Weber, Lukas Metzler, Patrick L. Fosso Tene, Thomas Brandstetter, Jürgen Rühe
Single-Color Barcoding for Multiplexed Hydrogel Bead-Based Immunoassays
ACS Appl. Mater. Interfaces 2022, ASAP
DOI: 10.1021/acsami.2c04361

Carmen J. Eger, Martin Horstmann, Simon Poppinga, Renate Sachse, Rebecca Thierer, Nikolaus Nestle, Bernd Bruchmann, Thomas Speck, Manfred Bischoff, Jürgen Rühe
The Structural and Mechanical Basis for Passive‐Hydraulic Pine Cone Actuation.
Advanced Science 2022, 2200458.
DOI: 10.1002/advs.202200458


Nathan Bentley, Frank Daniel Scherag, Thomas Brandstetter, Jürgen Rühe
Protein Repellent, Surface-Attached Hydrogels Through Spray Coating
Advanced Materials Interfaces 2022, 2102359.
DOI: 10.1002/admi.202102359

Julia K. Meinzer, Michael Henze, Chinnayan Kannan Pandiyarajan, Oswald Prucker, Wolfgang Bothe, Friedhelm Beyersdorf, Jürgen Rühe
Hemocompatible Surfaces Through Surface-attached Hydrogel Coatings and their Functional Stability in a Medical Environment
ASAIO 2022, 68, 56-63.
DOI: 10.1097/MAT.0000000000001426

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